As more people look for ways to unwind without alcohol, a growing number of supplements promise relaxation and stress support.
Two products that sometimes come up in this conversation are Santé Blends Original and U Relax by Calming Co.
While both use botanical ingredients associated with relaxation, they take different approaches to formulation, taste, and the overall experience.
Here’s how they compare.
What Is Santé Blends Original?
Santé Blends Original is a powdered supplement designed to create a noticeable sense of calm in about 15 minutes.
Many people use it as an alternative to a glass of wine in the evening, helping them relax without alcohol or next-day grogginess.
The formula supports the body’s GABA pathway, which plays a key role in calming the nervous system.
The formula includes a proprietary blend of eight functional ingredients (1,500mg):
- KSM-66 Ashwagandha
- GABA
- L-Theanine
- Noble Kava extract (30%)
- Passion Flower Extract
- Linden Flower Extract
- Magnolia Bark Extract
- Damiana Extract
It comes in single-serve stick packs designed to mix easily into water, tea, or mocktails.
What Is U Relax by Calming Co?
U Relax is a powdered drink mix designed to support relaxation and stress relief.
It contains a proprietary Ü Relax Blend (1,150 mg) that includes:
- Kava extract
- Ashwagandha extract
- Lemon balm extract
- L-Theanine
The drink mix is flavored (such as mixed berry) and contains ingredients such as steviol glycosides derived from stevia.
Effect Strength
One of the biggest differences between the two products is the overall formulation strength per serving.
Santé Blends contains a proprietary blend totaling 1,500 mg of active ingredients designed to support relaxation through multiple pathways.
By comparison, U Relax lists a proprietary blend totaling 1,150 mg.
While both products include ingredients associated with calming effects, Santé Blends provides a larger overall active blend per serving, combining eight botanical and functional ingredients.
Santé Blends is formulated so that one stick pack is typically sufficient for most users to feel a noticeable calming effect, often within about 15 minutes.
Some reviews of U Relax mention needing two packets to feel a noticeable effect, which may increase the effective cost per serving.
For people looking for a predictable single-serving evening ritual, this difference can be meaningful.
Taste and Flexibility
Another major difference is flavoring and how the product is consumed.
U Relax is sold as a flavored drink mix and includes stevia-based sweeteners.
While some people enjoy the flavor, others prefer to avoid sweeteners or flavored supplements.
Santé Blends takes a different approach.
It is unflavored and contains no sweeteners, which allows it to mix easily into a wide variety of drinks, including:
- herbal tea
- mocktails
- coffee
Because it doesn’t rely on added flavoring, many people appreciate that it doesn’t leave a strong aftertaste.
This also makes it easier to incorporate into an evening ritual.
Ingredient Quality: Why KSM-66 Ashwagandha Matters
Both products contain ashwagandha, an adaptogenic herb widely studied for its ability to support stress resilience.
However, Santé Blends uses KSM-66 Ashwagandha, one of the most researched ashwagandha extracts available.
KSM-66 is notable because:
- it is produced using a full-spectrum root-only extract
- it has been used in multiple human clinical studies
- it is standardized for consistent potency
- it maintains the natural balance of active compounds found in the plant
Many ashwagandha supplements use generic extracts that may include leaf material or non-standardized concentrations.
By contrast, KSM-66 has become one of the most widely studied forms of ashwagandha used in wellness supplements.
Formulation Approach
The overall formulation strategy also differs.
U Relax contains four primary ingredients associated with relaxation.
Santé Blends uses a broader botanical stack of eight ingredients, combining:
- adaptogens
- calming botanicals
- neurotransmitter-support ingredients
This multi-ingredient approach is designed to support both immediate relaxation and overall nervous system balance.
Comparison Overview
| Feature | Santé Blends | U Relax |
|---|---|---|
| Format | Unflavored powder | Flavored drink mix |
| Sweeteners | None | Stevia |
| Ingredient count | 8 ingredients | 4 ingredients |
| Ashwagandha | KSM-66 | unspecified extract |
| Serving strength | 1 stick typically sufficient | some users report needing 2 |
| Mix options | tea, juice, coffee, mocktails | flavored drink only |
The Bottom Line
Both Santé Blends and U Relax are designed to support relaxation, but they approach it differently.
U Relax focuses on a simple four-ingredient flavored drink mix.
Santé Blends takes a broader formulation approach with eight ingredients, premium extracts like KSM-66, and a flexible unflavored format designed for evening rituals.
For people looking for a drinkable alternative to alcohol that creates a noticeable sense of calm, Santé Blends offers a different experience. Learn more about Santé Blends Original.

